By Merrick Moseley BSc PhD, Alistair Fielder MD
This booklet offers a precis and synthesis of present matters and examine in the box of 1 of the main not easy paediatric eye stipulations - Amblyopia.
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Extra info for Amblyopia: A Multidisciplinary Approach, 1e
1996). However, research on amblyopia has proved to be more troublesome. Not only is there discord between the animal and human work, there is also no agreement between the various neuroimaging studies. g. , 1998; for reviews see Blakemore, 1990; Movshon and Kiorpes, 1990). , 1988). , 1999,2001). , 1999). In this chapter I hope to provide a coherent explanation for these disparate results, and in so doing determine whether or not area V I is the earliest site of dysfunction within the amblyopic visual system of humans.
They concluded that the distorted vision of human amblyopes relates to cortical deactivation in extrastriate visual areas. Imamura and co-workers noted that their results were consistent with reports that the pattern of ocular dominance columns in human area V I appears normal in both anisometropic (Horton and Stryker, 1993) and strabismic (Horton and Hocking. 1996) amblyopia. •MRI The tMRI studies of Sireteanu et al. (1998) also suggested that cortical activity within area V I is normal in human amblyopia.
Fronius, M, and Sireteanu. R. (1992). Localization disorders in squint amblyopia: horizontal line bisection and relative vertical localization. Klin. Monats. • 201, 22-9. Gingras. G.. Mitchell. D. E. and Hess. R. F. (1999). The spatial localization deficit in visually deprived kittens. 1111'. Ophthalmol. Vis. • 40, S54. Polat, U.. Sagi, D. and Norcia. A. M. (1997). Abnormal long-range spatial interactions in amblyopia. Vision Res.. 37, 737-44. Gstalder, R. J. and Green. D. G. (1971). Laser interferometric acuity in amblyopia.